Prof. Dr. med. Renke Maas

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie
Lehrstuhl für Klinische Pharmakologie und
91054 Erlangen

Telefon: 09131-8522754
Fax:      09131-8522773


Research areas:

A major interest of our group is the identification and characterization of new cardiovascular risk factors in experimental as well as in clinical settings. Currently we focus on the L-arginine-nitric oxide pathway and investigate endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine (AMDA) and its metabolism by the enzyme dimethylarginine dimetylaminohydrolase (DDAH). We determine ADMA and other major players in the L-arginine-NO pathway by stable isotope labelling and mass-spectrometric methods.

A further area of research are molecular and genetic reasons therapeutic failure and adverse effects of cardiovascular drugs.