Prof. Dr. Jörg König

Institut für Experimentelle und Klinische Pharmakologie und Toxikologie
Friedrich-Alexander-Universität Erlangen-Nürnberg
Fahrstr. 17
91054 Erlangen

Tel:  +49 (0)9131 85-22077
Fax: +49 (0)9131 85-22773
Arbeitsgruppe Koenig

Research areas:

Transport processes across membranes are important for the uptake, the distribution and the elimination of drugs. In the focus of our research are cellular models for investigating the molecular nature of human uptake transporters and export pumps. We used single-transfected cell lines for the analysis of uptake transporters or export pumps and double- and multiple-transfected cell lines simultaneously expressing one or more uptake transporters together with an export pump for the analysis of vectorial transport processes.  
Our research mainly focuses on the following topics:
 - what are the functional consequences of genetic variations in genes encoding transport proteins.
 - elucidating the role of transport proteins in drug-drug interactions.